IVF is considered the most effective form of assisted reproductive technology. The procedure is conducted using the patient’s eggs and her partner’s sperm. In some cases the IVF procedure may involve using sperm or embryos from a donor. IVF is also used in when a couple needs to use a surrogate – a woman who has an embryo implanted in her uterus, and carries the baby to term.
One cycle of IVF takes about two weeks and the procedure involves several steps:
IVF is performed to treat infertility, after trying less invasive treatment options, including fertility drugs for the formation of egg or IUI (Intrauterine Insemination – when sperm are placed directly in the uterus near the time of ovulation.)
Often, IVF is used as a primary treatment for infertility in women over 40.
IVF may also be done in cases where there is:
Before beginning a cycle of IVF the patient and her partner will need to go through several tests:
At Motherhood Hospitals’ IVF Center, two embryos are usually transferred into the patient’s uterus and any extra embryos can be frozen for future use. Not all embryos will survive the freezing and thawing process, although most will.
Embryo transfer is a painless procedure It is done without anesthesia. In some rare conditions anesthesia might be required if sp, the doctor will inform you, prior to the procedure.
Cryopreservation or freezing can make future cycles of IVF less expensive and less invasive.
IVF involves several steps: ovulation induction, egg retrieval, sperm retrieval, fertilisation and embryo transfer. One cycle of IVF takes about two weeks, and sometimes, more than one cycle may be required.
STEP 1: Controlled Ovarian Hyper stimulation
The patient will be treated with synthetic hormones to stimulate the ovaries to produce multiple eggs, rather than the single egg that normally develops each month. Multiple eggs are needed as some eggs don’t fertilize or develop normally after fertilization.
The patient may be given medications:
It usually takes one to two weeks of ovarian stimulation before eggs are ready for retrieval. To determine when the eggs are ready for collection, the following checks are performed:
Vaginal ultrasound: this helps monitor the development of follicles where eggs mature.
Sometimes IVF cycles may be cancelled before egg retrieval because of:
If the IVF cycle is cancelled, the IVF specialist might recommend changing medications or doses to promote a better response in future IVF cycles. In some cases, the patient might be asked to consider an egg donor.
STEP 2: OPU (Ooctye/Egg pick-up) and Sperm retrieval
Egg pick-up or OPU is usually done 34 to 36 hours after the final injection and before ovulation. The OPU procedure is a day-care procedure done under anaesthesia, and is usually completed within 10 to 20 minutes. It is a simple surgical procedure performed under the guidance of ultrasound.
Some patients might experience cramp-like pains on the day of process which subside by the next day.
A sperm sample is sought from the patient’s partner on the morning of egg retrieval. Donor sperm also can be used. The sperm are then separated from the semen fluid in the lab.
STEP 3: Fertilization and Incubation
Fertilization is attempted using two methods:
In cases of severe male infertility, the embryologist can inject a single sperm directly into the egg by a process called
Intracytoplasmic Sperm Injection or ICSI.
In ICSI, a single healthy sperm is injected directly into each mature egg. ICSI is used when semen quality or number is low or when fertilization attempts have failed during prior IVF cycles failed.
Fertility medications are usually prescribed to stimulate ovaries to produce multiple mature eggs. With a transvaginal ultrasound-guided needle, the eggs are removed from the patients’ ovaries and placed in a petri dish for fertilization. If her partner’s semen does not contain enough motile sperm, sperm can be extracted from a testicle with a needle. If a sperm sample reveals too few sperm, a biopsy can be taken from testicular tissue in hopes that there will be sperm attached.
Next, a single sperm is injected directly into each individual egg.
The next day the eggs are checked to see if fertilization was successful. The fertilized eggs will remain in the petri dish for a few days as they continue to divide and become early embryos. Using a thin catheter, the doctor then places the embryos into the uterus.
The full IVF cycle takes about 15 to 20 days to complete – from the first day of treatment until embryo transfer.
STEP 4: Embryo transfer
Embryo transfer is usually done two to five days after egg retrieval.
The patient can have a light breakfast before the procedure.
If successful, an embryo will implant in the lining of your uterus 6 to 10 days after egg retrieval.
After the procedure.
Post the procedure, you will be moved to a recovery room to rest and have a meal. You can return home after 2 hours. Once home you can go about normal activities but be sure not to lift or carry anything that’s heavy. You will also be asked to try avoiding vigorous activity, as it may cause discomfort.
About 15 days after embryo transfer, the IVF specialist will advise a blood test to detect pregnancy. Success of IVF ranges from 38% to 40% at our center.
The hospital is good, thanks to Dr. Sunil Eashwar sir for helping us to make our dream come true with his excellent advice and on time treatment. Motherhood has helped me embrace a journey toRead more
Dr. Sunil Eashwar is a very good doctor. I’m happy to be guided by doctor and such a professionalist. I feel he is the best doctor. Firstly, I met Dr. Eshwar and he told meRead more
Sunil Eashwar is very nice and friendly doctor. Me and my husband wanted a child for 8 years. With the doctor’s guidance, I conceived in 6 months. I am very thankful to Miss Noor forRead more
We just want to thank Dr Madhav Reddy for her great support. She was very caring and supporting for normal delivery. We got our little one through normal delivery without any issues.Read more
I was very much blessed and pleased with my experience with Dr Regina, an obstetrician and gynaecologist at Motherhood Hospitals. The doctor responded to all of our queries. Our family is delighted. I would likeRead more
The hospital has well-experienced doctors and expert gynaecologists and paediatricians. The staff professionalism is exhibited in their duty with compassionate care towards the patient. I would like to share an experience with Dr Aarthi Bharath.Read more
The doctors are very friendly. The hospital facilities are good and the staff is helpful and took good care of me. I have recovered and feel healthy now. The nurses took care of me. ThankRead more
My due date was 3rd April and my husband had made arrangements in Motherhood- HRBR, as we had a good experience during our earlier visit for my mother’s surgery. On 9th March 8pm, we wereRead more
I am Mrs Kavitha Sathyavelu living in Bangalore, Banaswadi. I had a great experience @ Motherhood Hospital. On my first delivery we had a good support from all the staff and doctors who had supportedRead more
The doctors and staff are friendly, epecially Dr Madhavi Reddy are very helpful during our first consultation till the time of discharge and provided with good guidance and medication. She clearly explained all our doubtsRead more
at Motherhood India Hospitals
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